A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection

Brad K. Hulse, Hannah Haberkern, Romain Franconville, Daniel B. Turner-Evans et al.
bioRxiv. December 2020

CLIENT

Jayaraman Lab, HHMI Janelia

TOOLS

Adobe Illustrator, Adobe Premiere Pro, neuPrint, neuTu, neuVid, Blender, Cytoscape

LINK

Full Article

NY Times Article

DATA

Hemibrain connectome (Scheffer et al. 2020)

Contributions

  • Generated a catalog of 3D renderings for all neuron types in the Drosophila central complex (CX)
  • Created additional renderings to display specific circuit components
  • Produced animation to introduce the central complex brain regions and visualize an example pathway through the CX
  • Make 6 animations to show CX output pathways
  • Contributed to graphic design and layout on select figures
  • Standardize design elements across figures to make cohesive publication

Paper Summary

The Central Complex (CX) is an extensively studied area in the brain of Drosophila Melanogaster linked to orientation and navigation. This paper uses the hemibrain connectome to describe all CX neurons and circuits at synaptic resolution. It details insights revealed by the hemibrain connectome, including novel cell type, sensory input and motor output pathways, and network motifs underlying navigational computation.

Full Article
Figure 1 (B)
Figure 1 (C-D)
Figure 56 (Ci-ii)
Figure 56 (E)
Figure 6 (Bi-ii)
Figure 46
Figure 4-figure supplement 2
Figure 26 (Ai-ii)
Figure 7 (B)
Figure 8 (Ai-iii)
Figure 40-figure supplement 1
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