Cell types and neuronal circuitry underlying female aggression in Drosophila

Catherine E. Schretter et al.
eLife. November 2020

CLIENT

Rubin Lab, HHMI Janelia

TOOLS

Adobe Illustrator, Adobe Premiere Pro, neuPrint, neuTu, neuVid, Blender, Cytoscape

LINK

Full Article

DATA

Hemibrain connectome (Scheffer et al. 2020)

Contributions

  • Assisted with formal analysis of circuits underlying female aggression in Drosophila
  • Wrote custom Cypher and Python scripts to query hemibrain connectome data
  • Made animations and images to show neuron morphologies, synapse locations, and brain regions
  • Created Drosophila graphics to better illustrate data and behavioral analysis
  • Drew a schematic of the arena used during activation experiments
  • Created network diagrams and charts to display connectivity data
  • Assisted with layout and color design on connectome figures

Paper Summary

Fruit flies, Drosophila Melanogaster, exhibit aggressive social interactions when competing for limited resources. These behaviors are regulated by sensory cues from the surrounding environment as well as the organism’s internal state. Using activation experiments with behavioral analyses and the hemibrain connectome, this paper describes a set of connected neurons that drive female aggression in adult Drosophila.

Full Article
Figure 12-figure supplement 1
Figure 11
Figure 12

Drosophila Illustrations

Figure 9F
Figure 8
Figure 9-figure supplement 1

Video 8

Figure 7

Drosophila Arena Illustrations

Figure 1F and 1H
Figure 1-figure supplement 3B
Figure 5-figure supplement 1

Video 12

Figure 10
Figure 10-figure supplement 2
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